Studies on the mechanism of oxidative phosphorylation. ADP promotion of GDP phosphorylation

Studies on the Mechanism of Oxidative Phosphorylation

Kinetic and nucleotide binding studies have shown that submitochondrial particles from bovine heart possess three exchangeable binding sites for ADP or GDP. In order of decreasing affinity at neutral pH, these sites will be referred to as sites I, II, and III, and their respective dissociation constants as KI, KIr, and KIII. In oxidative phosphorylation experiments in the presence of saturating...

Studies on the kinetic mechanism of oxidative phosphorylation.

The kinetics of the synthesis of ATP from ADP and Pi by beef heart submitochondrial particles were examined. When Pi was the variable substrate positive cooperativity was observed, whereas if ADP was varied, linear double reciprocal plots were obtained. The analog of Pi, thiophosphate, was a noncompetitive inhibitor of ATP synthesis with respect to ADP, while the analog of ADP, AMP (CH2)P, was ...

Further studies on oxidative photosynthetic phosphorylation.

Studies on the Mechanism of Oxidative Phosphorylation. 8. Purification of the Reduced Cytochrome C Coupling Factor.

It seems likely that the mechanism of mitochondrial oxidative phosphorylation will be understood only after the components of the system have been separated and identified, and the mechanism of their action examined in detail. Experiments in this laboratory, therefore, have been directed toward the resolution of the oxidative phosphorylation system of beef heart mitochondria into its component ...

analysis of reading comprehension needs of the students of paramedical studies: the case of the students of health information management (him)

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